How Your Choice of Cosmetics and Clothing Could Increase Your Diabetes Risk                                                                

Your choice of cosmetics and clothing could surely increase your diabetes risk, according to researchers. Let us see how.

Cosmetics

Phthalates (pronounced as thal-ates) are commonly applied as plasticizers and are extensively used in a wide range of products such as cosmetics, detergents, food packages, clothing, and certain medical devices.

There is an association between phthalates present in cosmetics and plastics and the risk of developing diabetes, especially among senior citizens. Even at a highly modest increase in circulating phthalate levels, the diabetes risk is doubled. This precise conclusion is drawn by eminent researchers at Uppsala University in a study that was published in the journal titled Diabetes Care.

Although the results need to be confirmed in several more studies, they do successfully support the hypothesis that certain chemicals present in the environment can eventually contribute to the development of diabetes. 

Researchers have analysed the latest info fpallone calcio a 11 brandon aiyuk jersey rom the so-called PIVUS (Prospective Investigation of the Vasculature in Uppsala Seniors) study, which covered more than a thousand 70-year-old women and men in Uppsala.

In a physical examination of the study, participants were examined for FBS (fasting blood sugar) and several insulin measures. They, then, submitted their blood samples for the analysis of several environmental toxins, including many that were formed when the body breaks down the so-called phthalates. Most individuals in the study came into daily contact with phthalates because they are extensively used as carriers of perfumes in cosmetics as well as self-care products and as softening agents in plastics.

As expected, diabetes was more likely to develop in participants who were overweight and had high lipid levels in their blood. That said, the researchers successfully found a connection between phthalates levels in blood and increased prevalence of diabetes, even after adjusting for factors such as obesity, smoking, blood lipids, and exercise. Individuals with elevated phthalate levels had around twice the risk of developing diabetes in comparison with those with lower levels. Researchers also concluded that specific phthalates were eventually associated with disrupted production of insulin in the pancreas.

Most phthalates are used in cosmetics, scented candles, solid air fresheners, and certain self-care products. Hence, one needs to be cautious when using these products.

Clothing

Thousands of chemical substances are made use of in the manufacturing of clothes. Researchers at the University of Stockholm have studied if chemicals are present in the clothes people buy. Several chemicals associated with health risks were successfully identified. What’s worse, organic cotton, too, was not a guarantee for toxic-free textiles.

In a new thesis, sixty garments from Swedish as well as international clothing chains were tested. An initial analysis eventually found thousands of chemicals in these clothes, and nearly a hundred chemicals were identified at a preliminary level. Several of these chemicals were not on the lists of the manufacturers and are majorly suspected to be by-products, chemicals, and residues added during the transportation process.

In recent years, an increasing body of evidence from both human as well as animal studies have successfully displayed a close association between exposure to early, unfavourable life factors such as EDCs (or endocrine-disrupting chemicals) and the prevalence of type 2 diabetes in later life. The exogenous EDCs can eventually lead to disadvantageous metabolic consequences because they cause an interference in the synthesis, secretion, transport, binding, action, and lastly metabolism of endogenous hormones.

EDCs additionally have long-term adverse consequences on newborns, children, as well as adolescents by leading to an increased susceptibility to type 2 diabetes.

The most common EDCs related to diabetes include bisphenol A, phthalates, pesticides, parabens, chlordane compounds, among others.

EDCs are natural or synthetic chemicals. Because their structure bears similarity to steroid hormones, they can eventually interact with the receptors of oestrogen, progesterone, and androgen, interfering with aspects of the role played by endogenous hormones, including the biosynthesis, metabolism, transport, and elimination, or receptor-binding of endogenous hormones, thereby increasing the risk of endocrine and metabolic diseases in humans, such as diabetes. 

Let us look at two EDCs and their adverse effects:

• Bisphenol A

Bisphenol A (or BPA) is a major component when it comes to polycarbonate plastics. It is one of the foremost compounds that are identified as endocrine disruptors, which can eventually disrupt the functioning of the endocrine system. 

• Phthalates

These chemicals are classified according to their molecular weights. Phthalates that have a low molecular weight are primarily used in personal-care products as well as cosmetics, besides pesticides and food-packaging plastics. Phthalates that have a high molecular weight are usually used to enhance the flexibility and durability of plastics. Phthalates can migrate, leach, or even evaporate into indoor air as well as atmosphere, foods, and other goods, thereby becoming a source for human uptake as they are not bound covalently to the plastic.

Thus, EDCs are one of the diabetes causes because they disrupt the production of insulin in the human body. Diabetogenic EDCs may eventually exert their action on the impairment of insulin production at the level of the pancreatic β-cells. 

To Sum It Up:

EDCs (or endocrine disrupting chemicals), which are present in plastics, clothing and cosmetics, can lead to type 2 diabetes because they hamper the production of insulin by the pancreas. Two of the most common EDCs include bisphenol A (BPA) and phthalates. Extreme care and caution need to be taken when using these products because the chemicals present in them can cause type 2 diabetes, which is a metabolic disease with several complications. 

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